Embryonal Tumours with Multilayered Rosettes - basic biology and tools for translation Dr Jens Bunt (The University of Queensland Queensland Brain Institute) Embryonal Tumour with Multiple Rosettes (ETMR) is a highly aggressive type of brain cancer commonly diagnosed in infants. Tragically, fewer than five in every hundred children with this brain cancer survive more than two years after diagnosis as standard treatments seem ineffective. This could be due to the unique nature of ETMR cells: they resemble very specific immature cells found in the normal developing brain. To enable the identification of better drug targets, the developmental origin and underlying biological causes of ETMR need to be understood. The research In this new project led by Dr Bunt from the Queensland Brain Institute, experts in neurodevelopment and in childhood brain cancer join forces to discover what drives the development and growth of ETMR. To enable discoveries that can be further developed to targeted treatments, Dr Bunt will use samples obtained from the Queensland Children’s Tumour Bank to generate new preclinical models for ETMR. The potential outcomes Evidence gained during the consultation process will be used to inform the development and implementation of sustainable services for paediatric brain cancer patients and families to address unmet need, improve equity of access and reduce variation in long-term health outcomes. The research team • Dr Jens Bunt – The University of Queensland – Queensland Brain Institute • Marcel Kool – German Cancer Research Centre, Heidelberg, Deputy Head of Department of Pediatric Neurooncology, International Collaborator and expert in genomics of pediatric brain tumours including ETMR. • Professor Linda J Richards, The University of Queensland – Queensland Brain Institute – Deputy Director (Research) • CCABCR PhD Student • Caity Bridges – The University of Queensland, Research Technician Back Will you help children with brain cancer?By making a donation today, you are becoming an important part of the Children's Brain Cancer Centre. We cannot do this without you. Donate Once Donate Monthly Your donation will work wondersfor sick kids today.Would you like to donate monthly? Your donation of will work wonders for sick kids Your Details Have a PO Box or can't find your address? State*ACTNSWNTQLDSATASVICWA Country Afghanistan Åland Islands Albania Algeria American Samoa Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Côte d'Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guam Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hong Kong Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People's Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People's Democratic Republic Latvia Lebanon Lesotho Liberia Libya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Marshall Islands Martinique Mauritania Mauritius Mayotte Mexico Micronesia, Federated States of Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Northern Mariana Islands Norway Oman Pakistan Palau Palestinian Territory, Occupied Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Puerto Rico Qatar Réunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan, Province of China Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States United States Minor Outlying Islands Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Viet Nam Virgin Islands, British Virgin Islands, U.S. Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe < Back Your donation of will work wonders for sick kids Your donation of will work wonders for sick kids Your donation of will be charged on the of next month and the following months thereafter Your donation of will be charged today and on the of the following months thereafter Payment Details Credit Card Direct Debit MastercardVisaAmex Month*010203040506070809101112 Year*20202021202220232024202520262027202820292030 15th of every month 28th of every month What is CVV? What is Date of Debit? 15th of every month 28th of every month 15th of every month 28th of every month For more information please check our Terms & Conditions Your request is being processed. < Back Connect and follow Children's Hospital Foundation